Betting tip: Fiorentina have won their last two visits here and are unlikely to come away with nothing
Both of these sides lost 3-2 on Thursday night and defences will need to improve.
Fiorentina won 4-1 here last season and theiraway form has been impressive this season.
Bet365 make Inter Evens with Fiorentina priced at 29/10
Both these sides are looking to move on from disastrous Europa League matches on Thursday. Inter are out of the tournament following a poor 3-2 loss to Hapoel Beer Sheva. They were leading 2-0, but saw Handanovic dismissed and it went downhill from there. They picked up just a single win in their opening 5 matches which came here against Southampton.
Fiorentina are likely to qualify for the knock out stages, but a shock 3-2 loss to Greek side PAOK came as a surprise. They were fairly unlucky in that game crashing shots against the woodwork and being denied a couple of penalties, but Paolo Sousa's men need to bounce back.
Fiorentina sit 2 points above their hosts in 8th, but should be higher. Their home form has let them down with too many draws in Florence and they should be confident of extending their 6 match unbeaten run here.
They won 4-0 last time out in Empoli and have also picked up a 5-3 victory against Cagliari and they can be devastating on the road.
Sousa will have to make changes to his backline here with Nenad Tomovic suspended. Nikola Kalinic is likely to come back in, he usually drops to the bench in the Europa League.
New Inter boss Stefan Pioli picked up a late point in the Milan derby last weekend. His side continued to attack and got their rewards with a late Ivan Perisic strike. Gary Medel has picked up an injury though and will be missed. Inter's defensive midfielder will be out for two months and it's a huge blow to the new boss.
Striker Mauro Icardi has been in fine form and the wounds between the Argentinian and the fans appear to be starting to heal. He has netted 10 times this campaign.
Take the 5/6 for Fiorentina or Draw on the Double Chance market. The Viola should take something from this game as long as they take their chances.
Inter have one of the best defences in the league, but Inter are more attacking under Pioli and will use the width of the San Siro to attack their opposition. Back Both Teams to Score? Yes at 7/10 with Bet365
Finally, back the returning Nikola Kalinic to strike anytime at 15/8 with Bet365